Due to its importance in movement, parasite morphogenesis, and pathogenicity, the flagellar structure and composition attracted interest among parasitologists (reviewed in [18, 19]).
It plays an important role in parasite morphogenesis and pathogenicity (reviewed in Langousis and Hill, 2014; Vaughan, 2010).
The Rho-type GTPase Rho1, which functions upstream of Mpk1, was found to be essential for morphogenesis and pathogenicity (Martinez-Rocha et al., 2008).
In fungi, G-proteins and the cAMP-dependent PKA pathway regulate vegetative growth, morphogenesis, metabolism and pathogenicity (Bolker 1998; Lengeler et al. 2000; Yu 2006).
Here, we provide evidences that MoVam7, an ortholog of S. cerevisiae SNARE protein Vam7, exerts conserved functions in vacuolar morphogenesis and functions in pathogenicity of M. oryzae.
Since most human pathogenic fungi are dimorphic, with yeast and filamentous stages of growth, these types of genomic studies will provide further insight into genomic events and selective forces that shape chromosome evolution and impact mating, morphogenesis, pathogenicity and habitat speciation in fungi and other eukaryotes.
Modules within the genome encode proteins involved in DNA-binding, morphogenesis, and lysis, but none associated with pathogenicity or lysogeny.
Furthermore, as the yeast-to-hyphae transition is a key factor involved in C. albicans biofilm formation and pathogenicity, we investigated if the time-course of C. albicans biofilm morphogenesis under in vitro and in vivo conditions can be monitored with BLI.
H2O2-producing copper oxidases have been shown to have roles in morphogenesis, in the corn-smut fungus Ustilago maydis for example, a glyoxal oxidase is required for filamentous growth and pathogenicity [87] and a galactose oxidase is involved in fruiting body formation in the gram-negative bacterium Stigmatella aurantiaca [88].
The words virulence and pathogenicity are often used interchangeably.
However, its clinical role and pathogenicity has not been known.
