Sentence examples for morphogenesis and checkpoint from inspiring English sources

Xrs2, in S. cerevisiae, serves as a scaffold to recruit Pch2, a protein that has many meiotic functions, including axis morphogenesis and checkpoint control (Ho and Burgess 2011).

High content imaging of GFP-tagged proteins in each deletion mutant was able to associate changes in protein abundance and localization with particular mutants (Vizeacoumar et al. 2010), uncovering known and novel components involved in spindle morphogenesis and the spindle checkpoint.

The relevant hallmarks of M phase are the completion of the budding process, and thus the inactivation of the morphogenesis checkpoint and the gradual decline of B-type cyclin levels as the cell proceeds through the exit from mitosis following cytokinesis.

In budding yeast, the morphogenesis checkpoint and the DNA-damage checkpoint involve septins as GTP/GDP-binding proteins that sense and transmit the status of cytoskeleton organization to cell cycle connected proteins in the nucleus (Kinoshita and Takeda 2007; Petretti et al. 2006; and reviewed in Enserink et al. 2006).

ATM and ATR can subsequently regulate cell cycle by phosphorylating downstream kinases checkpoint kinase 2 (CHK2) and checkpoint kinase 1 (CHK1), respectively.

Their checkpoint functions are mediated partially by the checkpoint effector kinases called checkpoint kinase 1 (Chk1) and checkpoint kinase 2 (Chk2) [17].

Taken together with the hsl7 Δ suppression data, our genetic analysis demonstrates that the spt10 Δ slow growth can be suppressed by mutations that delay cell cycle progression at either the G1/S transition or the bud morphogenesis G2/M checkpoint.

Reproducibility and checkpoint recovery.

As control strains, wild-type (checkpoint proficient) and checkpoint mutants for DNA damage/DNA replication mec1 sml1 and spindle checkpoint mutant bub1 were used.

Levels of the Cdc28p /Clb complex are low, due to the presence of B-type cyclin inhibitors, and the genes in the morphogenesis checkpoint (the species we have studied here) are not active, due to the lack of a bud.

S and G2 phases are characterised by the degradation of the B-type cyclin inhibitors and the consequent accumulation of Clb1p and Clb2p, the emergence of a bud, and the subsequent activation of the morphogenesis checkpoint genes.