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This study indicates the feasibility of single-cell analysis in early therapy response evaluation of cancer cells in combination therapy, and should be followed by more vigorous testing in larger clinical trials.
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Even as some scientists and advocates for women began arguing that at least there should be a more vigorous test of the estrogen hypothesis, it retained its power.
That would allow it to curb the size of new loans, without increasing costs for existing borrowers.An alternative is more vigorous stress tests of mortgage lenders themselves, using stringent scenarios that assume interest rates rise sharply while house prices fall.
But hearing specialists worry that many deaf or hearing-impaired babies who fail the screening are not making it to the next level of testing — a more vigorous hearing exam in which an audiologist uses an EEG-like machine that records the brain's response to sound.
21 Other trials showing greater levels of success in changing quality of life or performance based assessments of mobility have tested more vigorous and resource intensive interventions.
In the current study, the main interest was focused on the effect of the species differences and graft resistence after implantation, where equine grafts performed best although only grafts with the more vigorous cleansing procedure were tested.
Before exposing patients with Type 2 diabetes to more vigorous exercise programs, the ADA and U.S. Preventive Services Task Force recommend exercise testing for silent myocardial ischemia (SMI) if 10-year cardiovascular risk exceeds 10% [ 169, 245].
In this context a negative IP-10 test may prompt a more vigorous search for other pathologies (e.g. using alternative diagnostic strategies including thoracoscopy), and reduce exposure to unwarranted or empiric anti-TB treatment and its attendant toxicity.
Patients with a diverse pattern of response had more vigorous SFMC proliferation than PBMC proliferation to all antigens tested.
Features of parkinsonism, suggesting the possibility of orthostatic hypotension and autonomic failure, should lead to a more vigorous pursuit of postural blood pressure measurements and autonomic function tests.
This could have been avoided if a more vigorous question selection process had been undertaken, that would include multiple pilot tests, focus groups and interviews to enhance content validity [ 48, 49].
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