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However, the opposite traits – a more ventral eye position, smaller head, thinner body, and larger caudal peduncle – are advantageous for escaping predators [35], [58], [59].
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The overgrowths typically appeared in or near the missing ventral eye region.
Other than the ventral eye phenotypes, yap nl13/nl13 embryos showed no overt phenotypes (Fig. 2G).
Our fate map omitted the ventral eye, where diminished image quality precluded reliable tracking.
These analyses also indicate that RA signaling is not required for patterning of dorsal and ventral retinal territories, but rather for morphogenesis of the ventral eye.
During Drosophila eye development, Ser first promotes growth and cell survival throughout the ventral eye region and subsequently, together with Dl it induces a conserved dorsal/ventral (D/V) growth-promoting organizer.
Two more ventral parietal opercular areas named OP2 (ventral posterior parietal operculum) and OP3 (ventral anterior parietal operculum) may be the neuroanatomical correlates of two ventral somatosensory areas of the parietal operculum as defined in the New World titi monkey that were termed rostral ventral somatosensory area and caudal ventral somatosensory area (Coq et al. 2004).
Within its polarization-sensitive ventral eye region is a band of ommatidia that differ from the rest by the orientation of their central rhabdomeres [ 84].
Dorsal and ventral eye halves were separated by a cut through the optic nerve head and separately embedded in epon plastic.
Not every cell was tracked, so domain boundaries are somewhat imprecise, especially in the ventral eye, where reduced image quality hindered tracking.
RPE deficits were observed in yap nl13/nl13 embryos as in other alleles, but these were restricted to the ventral eye around the open choroid fissure.
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