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Initial reports investigating X-linked loconsistentlytly showed reductions in sequence variation in non-African, derived strains [ 9, 12, 13], while autosomal loci appeared to have more variable reductions in sequence polymorphism in non-African strains relative to their African progenitors [ 14- 21].
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Sensory axon area was more variable and showed a reduction in heterozygous mice and an increase in homozygotes (Fig. 5D,E).
As expected, excluding the pair of more variable peptides results in the reduction in the variance attributable to the residualsand the site effect.
Triglyceride reduction is more variable and usually between10%and20%20%.
In contrast, expression of the Ey isoform led to more variable phenotypes ranging from a small reduction and disorganization of the eye (Fig. 4A, panels b, e and h, and [41]) to over growth (Fig. 4b).
The effect of model violation on accuracy for trees with two differentially lengthened branches was more variable; little change (or even a reduction in burden) was observed for ML and Bayesian inference without ASRV correction, whereas violating the model greatly decreased the accuracy of reconstruction by gamma-corrected Bayesian inference.
Although treatment of HIV-infected individuals with HAART has had a significant effect on the burden of IPD in children (51% reduction), and a more variable effect in adults, the risk of IPD remains 28 to 42-fold greater in HIV-infected individuals than in the healthy population [ 2– 6].
Basolateral tolbutamide exerted an effect similar to apical addition in WT tissue, but the reductions in Isc were more variable (data not shown).
In the contralateral paw, thermal withdrawal latencies were more variable, with the most reproducible finding being a reduction in thermal thresholds in the amitriptyline caffeine combination group.
Results using a tetrazolium dye reduction assay, however, gave somewhat higher and more variable values, particularly with tetraplatin.
This reduction in dynamic range was also associated with later and more variable Tmax suggesting that the radial CA uptake curves were artificially flattened by data averaging.
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