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Some patients had 2 or more underlying diseases or conditions.
All of the patients had one or more underlying diseases (Table 1).
First, patients with NNHCA-IE had more underlying diseases, which were mainly responsible for the poor outcome and masked the impact of inappropriate antimicrobial therapy.
Fifty-five (91.7%) had one or more underlying diseases: 55 had hypertension, 10 diabetes mellitus, two asthma, seven chronic obstructive pulmonary disease, five atrial fibrillation, four coronary artery disease, and 19 hyperlipidemia.
All these parameters are good markers of severity of the episode of ARF, and they may drive for sure the decision of the clinician to go further with NIV or pass directly to invasive ventilation, but they are overall epiphenomena of one or more underlying diseases.
Reasons may include that elderly patients have less immunity, may have drug resistance due to physiologic changes associated with aging, often exhibit more underlying diseases and cardio-pulmonary complications, their hematopoietic function recovers slowly, and combination chemotherapy has significant side effects.
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Canine pyoderma is usually secondary to one or more underlying disease processes which compromise the defence mechanisms protecting the skin from infection [ 4- 7].
Children hospitalized for pandemic (H1N1) 2009 were older and had more underlying chronic diseases than those hospitalized for seasonal influenza.
This was most likely due to the more severe underlying diseases in this patient group [ 10].
Over 90% of clinical complications were observed in wards admitting patients with more severe underlying diseases.
The Charlson index score was used to categorize comorbid diseases (weighted index of comorbidity; range, 0 6; higher scores indicate more severe underlying diseases) [ 26].
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more fungal diseases
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com