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To get a more unbiased analysis of the pattern of DNA ploidy across BC subtypes, we used quantitative DNA FCM data for 338 unrelated BCs also analyzed by gene expression microarrays and BAC aCGH.
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The array data have been analysed both according to the present annotation and independently of any previous annotation, giving a more unbiased approach of analysis, and all transcripts have subsequently been categorized.
In contrast, sequence evidence from randomly selected genes, analyzed phylogenetically, provides a more unbiased database amenable to statistical analysis.
A more rigorous level of quantitation that provides unbiased analysis over multiple sections of dendrites, giving the Pearson's coefficient values would strengthen the data.
Using stable liver transplant recipients for this analysis however results in a more unbiased view on the specific genotype contribution on ODTac pharmacokinetics.
The absence of control points for the fitting curve of the quadratic B-spline function is adequate for an unbiased analysis and the use of a quadratic model allows more freedom in expression trend identification.
The latter is the most widely used method for codon usage analysis, whereas the former has been recently demonstrated to produce more unbiased results because it takes into account both amino acid composition and codon degeneracy information [ 48].
We propose that the genetically more tractable rodent parasite offers a unique opportunity for an urgently needed systematic and unbiased analysis of protein kinase functions throughout the malaria life cycle in vivo, including during mosquito transmission.
Nonlinear analyses were performed by using a finite element analysis software, ANSYS, and the results show that the improved strategy is more unbiased and accurate.
A NeighborNet analysis (Fig. 5) indeed confirms this complex ancestral history and provides a more unbiased view of phylogenetic clusters.
Analysis of multiple circuits brain-wide in a disease model will allow a more unbiased 'screen' for deficits, less restricted by prior knowledge and assumptions of disease pathology.
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