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Merck found that in some cases it needed far lower doses -- which usually means fewer side effects -- than if using the more typical criterion of how much the patients could tolerate, said Richard Hargreaves, the company's executive director for imaging.
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This broad range of 1 to 20 migraines per month was used to keep as many patients as possible in the sample; however, we also conducted analyses using just the subset of patients with 2 to 14 migraines per month, the more typical headache frequency criterion used in migraine studies.
The definition includes three criteria: a) one or more typical symptoms (at rest or during exercise), b) objective evidence of cardiac dysfunction (at rest), and c) response to treatment directed towards CHF (in cases where diagnosis is in doubt).
We used minimal exclusion criteria, and therefore our participants should be more typical of the general population than studies selecting healthy participants (e.g. [ 14]).
It was anticipated that these types of research designs may provide information about patient populations more typical of those encountered in primary care settings eg with a broad range of inclusion criteria.
More commercial, more streamlined, more typical.
Today was more typical.
If only Beihe were more typical.
My husband was much more typical.
But Italy is a more typical case.
But the more typical reaction is ambivalence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com