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Alexis de Tocqueville complained that "It is impossible to conceive a more troublesome or more garrulous patriotism; it wearies even those who are disposed to respect it".
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In most cases the patients were described as being "very quiet" and neither more troublesome, difficult, or problematic than others.
A second discovery by Bradley introduced an even more troublesome complication the nutation (or nodding) of Earth's axis, which has an amplitude of about 8 seconds.
A more troublesome situation is bidentate (or polidentate) ligands in which a donor atom acts in a neutral form and the other one acts in an anionic form.
Otherwise, you might as well concentrate on the dandelions, or on more troublesome invaders like Japanese knotweed, burdock, plantain (plantago species), Japanese barberry, Japanese honeysuckle, garlic mustard and Oriental bittersweet.
The answer, and the result in November, will turn in large part on which is more potent: Mr. Obama's argument that he offers a way toward "a better place" for struggling middle class voters whom Democrats say Mr. Romney does not understand, or the more troublesome reality of the moment for voters as they ponder Mr. Romney's question about whether they are better off than four years ago.
"For many people, if they can't go on Facebook or Twitter or Instagram, it may be more troublesome than if they don't have water," says Benthien.
But juror research is a more troublesome issue than sending Twitter messages or blogging, Mr. Keene said, and it raises new issues for judges in giving instructions.
In addition, the identification of these sources of variation becomes even more troublesome when reliability is consistently low (or high) across studies.
Even more troublesome, he said, there were not enough cells or units to separate violent inmates from those like Mr. Geoghan.
What is more troublesome, she said, is when drug companies give doctors gifts or financial incentives that could be viewed as financial rewards for prescribing a drug.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com