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But the F.D.A. — guardian of arguably more trial data than any other entity in the world — appears stuck in the era of data secrecy.
Ultimately, more trial data may be necessary to substantiate the increased use of distal protection devices in infrainguinal interventions to justify the increase in cost, complexity, and potential risks associated with the use of this technology.
For further improvement of model performance and model calibration, more trial data and data testing are required here.
For further improvement of model performance and model calibration, more trial data and data testing are required for these crops.
Currently, only TNF inhibitors are licensed for such patients, but other biological agents may receive similar approval with more trial data in the future.
Regarding overall morbidity, we found no association with benefit or harm between groups, but the trial sequential analysis indicated it would be futile to obtain more trial data on this outcome.
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A brief hiccup in the discussions occurred recently when Amgen demanded to see more clinical trial data on Kyprolis, people briefed on the discussions have said.
However, more clinical trial data with adequately-powered, well-designed and advanced methodology will be mandatory to conclude whether ALC as a monotherapy or augmentation agent may be efficacious and clinically beneficial for depression.
Drug companies have been under pressure to release more clinical trial data since revelations that they kept information from antidepressant and other drug trials secret.
More clinical trial data addressing the exacerbation benefit is expected to be reported later in 2013.
Were another large SARS outbreak to occur tomorrow, clinicians would have no more clinical trial data on which to base treatment decisions than they had 2 years ago [ 11].
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