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Interestingly, in most reports, allelic losses of 18q are infrequent in early-stage tumours (e.g., small adenomas), but are common in primary colorectal carcinomas and nearly 100% of hepatic metastases arising from colorectal primaries, implying that chromosome 18q loss of heterozygosity (LOH) may contribute more to progression rather than initiation of colorectal cancer.
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Substance use is also a predictor of incomplete adherence to antiretroviral therapy [6], which in turn may lead to drug resistance [12], [13], as well as to more rapid progression to AIDS and mortality [14] [16].
In several studies comparing the two variables, corneal hysteresis was more strongly related to progression than CCT.
Transcripts differentially regulated in both mutants are more likely related to progression through the L/Z transition.
Opportunities for progression are more to do with the options provided by the qualification.
These effects would undoubtedly contribute to the more rapid progression to AIDS.
PTC C4d deposition is related to a more rapid progression to graft loss, suggesting ongoing antibody reactivity.
However, there was a suggestion that time to progression was more favourable with the gemcitabine combination.
Greater language barriers in one country may hamper the ability of early detection and contribute to progression to more severe complications.
In the elderly, death due to second malignancies was more frequent than death due to progression (Table 4).
7 Failure to screen for HIV in older persons likely contributes to late disease presentation and more rapid progression to AIDS.
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