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Similarly, even if the assumption of low frequency of significant interactions may become compromised in more targeted studies, such as the one of St Onge et al, this should not have a major effect on the results as the strongest genetic interaction pairs are effectively filtered out in the sequential estimation process.
Findings in mice can then guide more targeted studies in humans.
The comparison of the results of more targeted studies with the ones reported in the current study would be inappropriate.
This allowed us to gauge the likelihood that relationships found between drugs and genes in this chemical genomic approach are reproducible and worth pursing with more targeted studies.
Similarly, many studies report gene expression differences between different chicken lines after artificial infection, identified by genome-wide, microarray analyses [ 33- 35] or more targeted studies focusing on one or several genes [ 36- 41].
The functional significance and role in fertilization of these classes of proteins is unknown, but demonstration of their presence and activity in sperm is a necessary step towards more targeted studies.
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Blaser conducted a larger and more targeted study.
A systematic overview over miRNA regulome can contribute to more targeted study design and understanding of miRNA function.
Robert L. Redding, Jr., Washington, D.C. representative of the Automotive Service Association, noted in an email that most auto shops now use reusable towels and that trend is unlikely to change until there is a more "targeted study of wipes in the automotive shop environment".
These methods and resources were developed with the intention that they would be useful to researchers who wish to test a priori biological hypotheses, either within the context of a GWAS, or for a more targeted study such as studying specific addiction-related genes or fine mapping a region of genetic linkage for an addiction-related phenotype.
The second case study demonstrated that the results from this comprehensive survey of NHANES are comparable with a more targeted study focused on a single disease end point.
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more targeted literature
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more formal studies
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more clinical studies
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more biochemical studies
more sophisticated studies
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