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But if personalised medicine allowed smaller trials, and marketing to more targeted populations, drug companies may not have to be so big.Before and afterGetting a drug to market is one thing; a growing problem is keeping it there.
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Under a plan proposed by the Texas Higher Education Coordinating Board, the eligibility pool for the state's largest need-based grant program would be reduced and the award decreased, allowing financing to stretch farther in a more targeted population.
Owing to the observed heterogeneity of effects among various disease states and the hypothesized anti-inflammatory mechanism of action, a clinical trial would preferably be performed among more targeted disease populations such as patients with sepsis.
Further studies should consider longer trial duration, higher intensity exercise, use of function-based scales as appropriate, and a more targeted study population to reduce group variability when assessing outcomes in interventions designed to improve functional task performance.
More targeted research in this population and other population subgroups not well represented in this study (e.g., rural/remote and culturally and linguistically diverse women) is required to adequately assess their unmet needs.
Identification of the most potent constituents should lead to more targeted regulation to protect populations at risk.
This may be challenging, but follows a predicted pattern of the need to develop more targeted messages for specific population groups [ 33], and reinforces the call for decision aids [ 18].
Several annual campaigns were organized, directed at the general population, as well as more targeted campaigns to reach vulnerable or key populations at higher risk [ 14].
7 Clinicians may want to consider whether these populations need more targeted advice to help make access to important lifestyle advice more equitable.
Identifying human socioeconomic or behavioral risk factors may enable a more refined definition of the highest risk populations for more targeted control efforts.
Another reason for the noted difference in coverage might be a variation in the definition of uptake, and more particularly the targeted population (i.e., the denominator).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com