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Both LAIV strategies prevent more symptomatic cases than the strategy which uses only TIV, most noticeably for low annual vaccination coverage.
In Figure 6a (only TIV vaccination), scenario 2 would prevent 12.7 million more symptomatic cases in 10 years than scenario 1 would; in Figure 6b (LAIV and TIV vaccination) and 6c (only LAIV vaccination for children from 2 years of age), scenario 2 would prevent 21.5 million more symptomatic cases in 10 years than scenario 1 would.
The hospital based diagnoses of branch retinal vein occlusion in this study might have conferred a selection bias in favour of the enrolment of more symptomatic cases, patients most likely to respond to treatment, and patients without other health problems that might deter them from seeking care for poor vision.
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Estimates based on health care resource utilization in this setting may underestimate true prevalence and probably be biased toward the more severe and symptomatic cases.
Infection with Borrelia spp. is the most common vector borne infection in Europe with an estimated more than 60,000 symptomatic cases annually and a reported incidence from Germany of about 1 per 1,000 population [ 1].
The authors discuss that these decreased levels of transmission at some areas without proper immunization could result in shifting of infection to older age strata, resulting in more symptomatic and fatal cases [ 17].
The differences in the proportion of newborns with a birth weight of <2500 g and that of SGA were statistically significant, with the differences being more significant in symptomatic cases.
Volunteers who are deemed potentially eligible will undergo a semiflexed posteroanterior x-ray of their painful knee (the more symptomatic knee in cases of bilateral eligible knee pain) at one of six trial radiology centres unless they can provide their own such films from within the previous 12 months.
However, bilateral presentation of pain was more frequently observed in symptomatic cases.
From 2007 to 2010, (the southern part of) the Netherlands experienced a large Q fever epidemic, with more than 4,000 reported symptomatic cases.
During the years 2007 201010, (the southern parts of) the Netherlands experienced a major Q fever epidemic, with more than 4,000 reported symptomatic cases.
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