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Muscle tissue shows the lowest tolerance to pressure injuries, compared with more superficial tissues.
Pressure-related deep tissue injury (DTI) represents a severe pressure ulcer, which initiates in compressed muscle tissue overlying a bony prominence and progresses to more superficial tissues until penetrating the skin.
This may be explained by the fact that urate deposition also occurs in other places besides tendons such as in the articular cartilage, subchondral bone, synovial membrane, capsular and periarticular tissues, and in areas of decreased temperatures such as in more superficial tissues of the extremities.
In particular, in the case of brain imaging, addressed to detection of hemoglobin content and oxygenation, time-domain measurements have been proposed as a means to reach deeper structures (brain cortex) uncoupling for the masking effects caused by more superficial tissues [ 2– 7].
It is still debated to what extent the more superficial tissues influence the measurement, e.g. Germon et al found a significant effect of varying the extra cranial perfusion [ 26] while others report negligible contributions from the extra cranial tissues [ 27, 28].
Heat transfer from the skin surface into deeper tissues is inhibited by the subcutaneous fat, which acts as a thermal insulator, and by the increased blood flow in more superficial tissues which cools the tissues by transporting away the heat [ 17].
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However, the technique tested involved infiltration via wound drains which deposited local anaesthetic in a more superficial tissue plane than the subpectoral plane and did not use a continuous infusion.
In addition to the two-dimensional layout of the dendrite, this spatial separation of inputs might also be present in the z-direction: In the lobula plate, motion signals from local elements that are sensitive to vertical motion have been argued to terminate in more superficial tissue layers than those sensitive to horizontal motion [ 28].
However, it has been recently proposed that the more superficial connective tissue layers might be more important, based on the entwining of connective tissue around the acupuncture needle in animal models and ultrasound imaging in humans [ 17, 18].
Alexandrite and diode lasers do not affect the more superficial epidermal tissue and were designed to prevent potential side effects by penetrating deeper layers of the skin.
With this in mind, the frequency of 1.0 MHz is more suitable for deep tissues, while 3.0 MHz is more appropriate for superficial tissues [31].
More suggestions(15)
more superficial structures
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more complex tissues
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more sporophytic tissues
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more superficial ulcerations
more radioresponsive tissues
more superficial publications
more accessible tissues
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