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More subtle difficulties in learning and memory may not become apparent for many years but provide the bulk of the societal burden following neonatal HIE.
While this is likely suitable for some forms of geriatric depression and dementia, these measures may not be sensitive to the most common executive or processing speed deficits or to the more subtle difficulties in long-term memory retention (ie. measured on neuropsychological testing) typically reported in non-geriatric depressive disorders [ 3, 4].
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There are also more subtle or surprising difficulties.
In these circumstances, translations may lack interpretation, because children have difficulty conveying more subtle aspects of communication such as cultural and nonverbal aspects: " Perhaps a child can convey the wrong message" (II8. Mediator.
A more subtle yet powerful barrier is greater difficulty demonstrating return on investment.
The difficulty of isolating and measuring these more subtle effects makes them impractical as regulatory endpoints.
People who have suffered TBI may also have difficulty with understanding or producing spoken or written language, or with more subtle aspects of communication such as body language.
Perhaps the difficulty of explaining love adequately is that in order to explain something you need another something more subtle and comprehensive with which to explain it.
It's more subtle".
Mimes are more subtle.
It was more subtle.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com