Sentence examples for more subtle differentiation from inspiring English sources

Employing a finer-grained temporal paradigm might yield a more subtle differentiation between all the emotion categories in further research.

To further test for more subtle genetic differentiation, we used STRUCTURE 2.3.4 [ 42] and the Evanno method [ 43] implemented in STRUCTURE HARVESTOR [ 44] to detect differentiated populations (k).

We hypothesized that the application of correlational analyses to resting-state fMRI data in a single study can enable the characterization of task-independent patterns of functional connectivity with more subtle regional differentiations.

Better management and more subtle ticket-price differentiation could reduce congestion.

We showed that plasma protein profiling allows a more subtle phenotypic characterization and differentiation of people with otherwise similar phenotypical features such as BMI or insulin levels.

Unfortunately, to date there are no Xenopus-specific anti-CD4 Abs available, thus preventing us from examining whether b2m KD induced more subtle defects on thymocyte differentiation.

For assessment of more subtle differences in cell differentiation, primary neurospheres that had been cultured for 7 days (see above) and neurospheres from passage 3 were gently triturated and plated on 24-well plates (40 cells/μl) containing coverslips coated with 1 mg/ml poly- d-lysine (Sigma, Germany) according to modified protocols [ 5, 7].

Taken together, RED-seq not only detects large differences in chromatin accessibility between distinct cell types (ESCs vs MEFs) but also tracks more subtle changes that occur during differentiation (control vs Oct4 KD ESCs).

Complete switches in the dominant TSS were reported to occur in over 300 genes during differentiation with more subtle shifts being detected in over 1300 others [ 68], suggesting that the TSS fingerprint (the relative abundance of the TSS variants of each gene) within the transcriptome is a genetic marker for cellular type (phenotype).

Investigating co-occurrence of multiple histone marks facilitates the differentiation of more subtle features in chromatin state, such as identifying tissue-specific strong and weak enhancer regions (Ernst et al., 2011) and changes in co-occurrence patterns between evolutionarily distant species (Ho et al., 2014).

Next, to test whether we could observe more subtle changes in chromatin structure during cellular differentiation, we differentiated ESCs by RNAi-mediated knockdown (KD) of the ESC pluripotency TF Oct4.