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Increasing the power may have resulted in more subtle correlations, although we have found some correlations to be significant (certain effect) and others not (possible effect).
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Unlike previous work, our approach does not require that genes within a set are highly correlated in at least one biological condition; they may be, but differential regulation can manifest itself in significant but more subtle correlation shifts.
The team's computer program decided whether a drawing was a genuine Bruegel based on statistics of how frequently the artist made a stroke within 15 degrees of vertical or 15 degrees of horizontal, along with more subtle statistics on correlations between nearby strokes.
The small number of patients could make our study underpowered to reveal more subtle findings, such as correlation between clinical features and functional connectivity, although our cohort was sufficient to disclose strong statistical significance.
In contrast, the transcriptional response of the ammonium-limited cells to an ammonium impulse was more subtle, with the Pearson correlation coefficient between each sample and that from the preceding steady state always >0.95.
For inferring more subtle changes in distribution of correlation coefficients, future work may use other methods that are capable of revealing local fluctuations of distribution functions.
This is all algorithmically generated, Hallett told me, and it's based less on what people say explicitly on Twitter (though that's a component) and more on using "massive amounts of subtle correlations" that suggest implicit details about users' demographics, interests and habits.
These calculations confirm that the neuronal coding is much more subtle than the straightforward intuitive optimization of input output correlations.
A simple correlation analysis captures only very coarse features of data and misses more subtle patterns.
Based on our correlation analysis above, we hypothesized that this mutant may have some more subtle defects that cannot be compensated for by the remaining family members.
It's more subtle".
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