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Once again, increasing sample number through integrating datasets results in a greater number of significantly differentially expressed genes, between the Sorlie et al. basal and luminal-A or the more subtle comparison of luminal A and luminal B subtype samples, at a given FDR (Additional file 4).
In the cases of GPCR and enzymes, almost no structure is found by the sequence kernels, which, as alluded to above, was expected and suggests that more subtle comparison of the sequences would be required to exploit the information they contain.
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But a little later in child development, those stark oppositions give way to more subtle comparisons.
The tale of German and British soldiers playing football in No Man's Land to celebrate Christmas in 1914 is an immortal (if perhaps fictive) example.But sometimes these comparisons are more subtle.
The scale has been adjusted for this superimposition to detect more subtle change among average to average comparison.
In comparison, there is a more subtle difference between the partitions of Day 12 and Day 12 with LDH inhibition.
By comparison, Chevron's troubles are more subtle.
When treatments under comparison differ appreciably, small samples will be sufficient; for more subtle differences larger numbers of patients need to be recruited.
It is noteworthy that the 1-year comparison window in this study may not be sufficiently sensitive to detect more subtle differences that have evolved.
This indicates that comparisons of ratios are not always consistent enough across technologies to identify more subtle differences in a sample.
Comparison of the Gibbs energy profiles employing 1 a and 1 b, shows a much more subtle difference between these two analogues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com