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Larger cohorts will be necessary for a more substantial statistical power concerning its prognostic relevance for AC.
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Bone lead levels measured by in vivo KXRF were begun in some research laboratories in the 1980s, but it was not until the mid-1990s that reports began to emerge of KXRF-measured bone lead levels in relation to potential health indicators from epidemiologic studies with large enough sample sizes (e.g., 100 or more subjects) to have substantial statistical power.
The adjusted analyses not only indicate a moderately larger treatment effect but also provide strong statistical evidence for a more substantial treatment effect than can be claimed using an intention-to-treat analysis.
Meta-analyses for both ANC coverage four or more visits and perinatal mortality had substantial statistical heterogeneity.
A formal assessment of statistical heterogeneity was done by using the Q statistic and the I 2 statistic; the combination of both tests is more sensitive to detect the likelihood of substantial statistical heterogeneity.
Although we cannot exclude diminished statistical power to detect a more substantial age impact because of limited patient numbers in much older cohorts, more than half of our patients were older than 60 years and approximately 20% even ⩾70 years.
The group-specific clustering of PHGPxs was much more substantial in the neighbor-joining tree, albeit the statistical significance of some branching nodes could not be supported by bootstrap analyses.
At a genome-wide significance of 10−8, this additional restriction resulted in only a marginal decrease in statistical power, although this decrease was more substantial at less stringent significance thresholds.
Indeed, this brand had approximately two times as many genes meeting our statistical threshold, suggesting that it induced a more substantial overall cellular effect.
Importantly, statistical tests indicated that recombination seems to be more substantial within groups than between (Table 1, 2), implying that there is genetic isolation between groups A and B owing to DNA sequence divergence.
More substantial!" Pavarotti said.
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