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On a more substantial size, the answer is less clear.
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This study only evaluated relatively small changes in sample size, we expect much larger effects on results for more substantial sample size changes, as shown by simulation [ 28].
The characterization of renal stem cells during mammalian development has been focused on the metanephros because it becomes the permanent organ and is much more substantial in size.
Current estimates suggest a 17-hr generation time under selection and clones have to reach a much more substantial colony size before the rarer secondary purR or purO mutation could be realized.
Overall, BioBin can be used as a filtering mechanism to group data and evaluate rare variant burdens between two groups, but requires a more substantial sample size to gain power to detect significance.
Moderator analyses indicate even more substantial effect sizes when the animation is representational rather than decorational (d = 0.40, 95% CI 0.26 0.53), when the animation is highly realistic, e.g., video-based (d = 0.76, 95% CI 0.39 1.13), and/or when procedural-motor knowledge is to be acquired (d = 1.06, 95% CI 0.72 1.40).
The effect of dimension on estimated efficiency scores was more substantial than that of size.
Analysis of protein disorder in several genomic sequences has shown that the occurrence of disordered regions of substantial size (more than 40 residues) is surprisingly common in functional proteins [ 23, 62].
The documents had been due earlier, but bankruptcy Judge Brendan Shannon agreed to extend the filing period after Fresh & Easy lawyers asked for more time due to "the substantial size, scope and complexity of this Chapter 11 case".
This demonstrates the more substantial trade-off between litter size and birth mass as was observed already from the phenotypic correlations.
There's more substantial dicks: there's one the size of a coke can..
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CEO of Professional Science Editing for Scientists @ prosciediting.com