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In contrast, monovalent antigens fail to induce BCR clustering, leading to more substantial requirements of both Syk and Src family kinases.
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Our inspectors have also identified more substantial safety requirements such as installing fire doors and automated fire alarm systems, establishing fire protected exits from factory buildings, and strengthening of columns in the buildings.
More substantial inflammation may require topical or systemic corticosteroid therapy.
The types of impartiality implied by both of these more demanding versions of the universalizability requirement are likely to be considerably more substantial than the formal consistency required by the minimal version.
The assessment did reveal some weaknesses in the original project design including the need for more substantial toe protection and periodic maintenance requirements.
More substantial!" Pavarotti said.
Or something more substantial?
It is time for something more substantial.
The markets had wanted something more substantial.
More substantial progress may take a generation.
Today their resources are more substantial.
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