Among women, high levels of strain at work can have even more substantial effects on physical inactivity if combined with the demands of family responsibilities [ 19, 43].
This would explain that in DCM only those cells exposed to more substantial and continuous physical stress (like cardiomyocytes) develop the disease and with late onset, while in the progerias the defects are systemic and/or appear earlier.
Taken together, this suggest that ParkFit was a safe intervention but that the programme needs to be adjusted to achieve more substantial increases in physical activity that translate into tangible health improvements.
Over the course of the previous decade, Russian military and intelligence theorists began to elaborate more substantial ideas for non-physical warfare – claiming that Russia was already under attack, along similar lines, by western NGOs and media.
Here, the volume growth over the last four years has been even more substantial because we set up physical supply locations in Panama, Houston, Algeciras and ARA (Amsterdam, Rotterdam and Antwerp) which is the second-largest bunkering group of ports in the world.
Eliot was so powerfully grim, atmospheric, authoritative; Hughes's early poems made the physical world look more substantial.
Suppose the real universe is something we can't see and all the glittering chains of galaxies are no more substantial, no more reliable guides to physical reality, than greasepaint on the face of a clown?
Research addressing social and psychological needs during physical illness has become more substantial in recent decades [ 1, 3].
The Internet presence for the campaign is more substantial than for previous campaigns by the Visiting Nurse Service, which provides physical therapists, medical social workers and certified home health aides in addition to registered nurses.
Third, our observations were made in a 2-year follow-up study, whereas the previous studies 18 19 investigated function over a period of 9 12 years, in which deterioration of physical function is likely to be far more substantial.
