Sentence examples for more substantial challenge from inspiring English sources

So I want to play more Godfather II, but not until it provides a more substantial challenge and experience.

But he says, the more substantial challenge now is getting people, regulations and the driving environment ready for the change.

She now faces Serena Williams in the quarter-finals today and can expect a considerably more substantial challenge than that posed by Myskina.

A more substantial challenge arises from the fact that 126 years after his death, Wagner remains a polarizing figure because of his radical nationalism and anti-Semitism.

Leiter and Weisberg do see a more substantial challenge in Nagel's skepticism about evolutionary explanations for our ability to discern truth in ethics, logic and math.

But the resistance in the greenest of green countries underscores a more substantial challenge to the international effort to drastically reduce fossil fuels in the world's energy supply: workers and retirees, local economies and communities still depend on the fuels the rest of us hope to let go of to preserve the planet for our children and our children's children.

Ki-67 labeling index presents more substantial challenges, but important guidelines for this test are under development [ 7, 83– 83].

For clinicians and clinical trials researchers, fluctuations in QOL that do not meet the MCID threshold may not be noticeable by patients or their families yet should be monitored to determine whether more substantial challenges arise and require intervention.

Thus, a more substantial immunological challenge, or a series of smaller challenges, resulting in prolonged activation of the immune response, may uncover underlying genetic variation for deployment costs.

Epidemiologic trends, aging and evolving population demographics along with technological advances in endoscopy, diagnostic and surgical technique will make the management of patients with bladder cancer in the near future a more substantial economic challenge [ 7, 8].

"But there are plenty of companies here that could survive a crash".The more sustainable the growth, though, the more substantial the challenges.