The genetically engineered, humanized anti-CD33 antibody HuM195 has demonstrated modest activity against overt relapsed acute myeloid leukemia (AML) and more substantial activity against minimal residual disease in acute promyelocytic leukemia.
The more substantial argument against quantitative easing is that purchases of securities would be ineffectual, given Europe's bank-based financial system.
"Action is going to be necessary, and if they don't take significant action, we know from past votes that there will be a much more substantial vote against it next time".
And yet the evidence for more substantial bias, against both individuals and research topics and directions, is hard to dismiss — and the hostility that some social psychologists have expressed toward the data suggests that self-correction may not be an adequate remedy.
More substantial resistance against MAO-A, which may be reached by deuteration at the α-position, potentially increases the absolute uptake by up to threefold after 30 min and almost tenfold after 60 min (as seen when inducing complete inhibition of MAO-A by clorgyline, Figure 3).
She urged any other women who were assaulted by Cosby in New Jersey to come forward in order to build a more substantial case against him.
Although Wilder worked on "The Matchmaker" for years, it's not one of his more interesting pieces; it contains all the whimsy and strained humor that he disciplined himself against in more substantial plays, such as "Our Town" (1938) and the overlong but fascinating "The Skin of Our Teeth" (1942).
But in another example of the gradual chiselling away of already-fragile legal precedent, some suspect the case is returning to court primarily because of its ability to have an impact on two more substantial affirmative action cases pending against Harvard University and the University of North Carolina.
Another way to look at it is that the inmates' spontaneous burst of rioting turned instantly into something more substantial: a full-blown revolt against miserable prison conditions, a seething that had been building for a long time because of ignored grievances about overcrowding, rigid censorship, bad food and shabby medical care.
This is a problem best solved by police surveillance, intelligence and border guards, not by the armed forces.The Dutch contribution to sanctions against Russia is more substantial.
