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Despite of the limited structural information for Sirtuin/inhibitor complexes, more and more structures of different Sirtuin isoforms reveal their subtle differences.
It's not like the rest of the country, where there are no more structures of government".
Significantly, with more structures of α-conotoxins also becoming available this enables ready comparison of their similarities and, more notably, of their subtle differences, which dictate subclass selectivity.
In summary, with more structures of Nav channels solved in the near future, computer simulations are expected to play more important roles in connecting the molecular details and macroscopic experimental measurements for these channels.
We agree with the comment of the reviewer, and would like to add that far more structures of Rab-RabGEF pairs are needed before we can make any definitive statements on GEF classification.
It is not helpful to say that selection bias might exist in a cross-sectional study (or in any design) or that one design allows for more structures of bias than another.
Similar(53)
The difference in the response rate between the two parts of the survey was attributed to a more structuring of the cattle than the sheep livestock (more hobby sheep breeders).
But the job of the future is to assemble those pieces into more and larger, more complex structures – of knowledge, of machines, of systems.
More recently the investigation of more structures beyond simple crossbars have been investigated by nanoimprint lithography.
Another line of research is to explore methodologies that could move toward more structured techniques of exploration.
But it would have been stronger with a larger, more structured set of evidence.
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CEO of Professional Science Editing for Scientists @ prosciediting.com