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A less severe version of this type of interference, that can decrease the efficacy of selection in sexual organisms, occurs when a locus under weak selection is tightly linked to a more strongly selected locus (i.e., Hill-Robertson Effect; [ 5, 6]).
Substitutions at buried sites are more likely to be disruptive than substitutions at exposed sites, and are therefore more strongly selected against.
Based on this sample, it is possible that recombination between more divergent T3SSs is more strongly selected for than similar recombination between housekeeping genes.
This should be even more strongly selected in colorful carotenoid-based bird species, in which additional allocation of these compounds for feather pigmentation demands an even larger consumption of carotenoids.
One is tempted to speculate that either these spacers are intrinsically more stable than the others for some unknown reason, or that they are more strongly selected for and thus rarely lost.
Again, patrigenes are more strongly selected to discriminate (unless r qq = 0).
Similar(39)
Such mosaicism most often is found recurrently when the presence of a mutation in one or more tissues is strongly selected against via lethality or when there is significant selective advantage for stem cells that have lost the disease-causing mutation.
Alleles considered neutral or nearly neutral (for mutation accumulation), or under negative selection small enough to be traded-off for a positive effect at younger ages (for antagonistic pleiotropy) may be more strongly negatively selected than thought.
Persistent and strongly selected epitopes were more likely to peak over 1000 SFC/106 PBMC than those experiencing weak selection (p = 0.004 for both comparisons, Fisher's exact test).
Naturalistic designs may have more clinical implications than investigations of a strongly selected sample of patients.
This indicated that these two chromosomes may carry more QTLs or genes related to important agronomic traits that were strongly selected in breeding [12].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com