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When considering a more stringent selectivity cut-off value, namely 3 pIC50 units, we obtained a set of 61 compounds.
These results indicate that S5a has more stringent selectivity of ubiquitinated target proteins than does HR23B.
Similar(55)
The lack of utilization of host-derived or supplemented fatty acids may be due to the more stringent substrate selectivity of these nrPKSs or, in the case of the fed substrates, excessive catabolism or a failure in uptake/compartmentalization by the yeast host.
The glycoform preference discovered in this work is in line with this finding and suggests a more stringent substrate and glycoform selectivity of EndoS compared with EndoS2.
Our selection strategy was more stringent.
Thus, selection criteria were more stringent in the latter study.
Some states are more stringent.
More stringent corporate governance rules.
They should be more stringent".
Brooker feels NGOs should be more stringent.
But this year, the criteria were more stringent.
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