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Personally, I think more stringent filters on photos that include over six friends tags but don't show any faces would help.
This procedure amplifies both the valid and invalid data, though, so researchers have to apply more stringent filters to their results.
The 3,020 clones whose 5' end did not match a FANTOM3 TU are those whose sequence satisfied our quality criteria for clustering, but were discarded by the more stringent filters of the FANTOM3 RTS.
Since sensitivity measures the inclusion of true positives in the estimate, as more stringent filters are applied, the sensitivity suffers: filters only remove publications from the raw result returned by the search engine, so raw results will contain the most true positives.
In the future, more stringent filters are needed for RNA editing prediction to remove this type of mapping errors.
This suggests that thermodynamics was not the principle criterion for nucleoside selection during evolution but rather provided only a weak constraint acting in concert with other more stringent filters such as stability and concordance of structural properties with functional needs.
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If a more stringent filter is applied, by removing annotations with three characters or less, recall drops by 12.6 percentage points while precision only improves slightly, by 2.6%.
We observed that the higher miRNA target site density in transcripts containing the motif increases with more stringent filtering.
Therefore more stringent filtering conditions were applied than for the original PCR: genes with differential expression in more than 30% of the tumors at a tumor-to-normal ratio of 1.2 were removed from the dataset.
Thus, more stringent filtering of the reference genome was required.
We recommend controlling for homopolymer false INDEL calls with a more stringent filtering criteria.
Related(20)
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