Sentence examples for more stringent expression from inspiring English sources

Larger values represent a higher propensity for CNV coupled with more stringent expression constraint (i.e., small Vg/Vm).

A more stringent expression level cutoff was placed where the discrepancy dramatically drops (dashed line at ln TPM) = −1.6).

Instead, a high abundance of transcription related genes could be responsible for the more stringent expression regulation.

Researchers who wish to increase the accuracy could apply more stringent expression level cutoff to the dataset.

Based on this figure we defined a more stringent expression level cutoff, where the discrepancy between the parental biases inferred by RNA-seq and pyrosequencing drops dramatically.

We therefore excluded new gene models that were upstream of the known genes without a H3K4me3 peak, or did not meet more stringent expression and splicing criteria (see Materials and methods).

But his own generation, Mr.Yu lamented, is more caught up in commercial pursuits and faces more stringent limits on expression.

For our analysis we used more stringent requirements for expression (see below) than previous work.

In general, array CGH must be more stringent than gene expression analysis because it is required to detect single copy changes and, while the copy number of a gene, unlike the expression level, is expected to be identical in two samples, this is often not the case due to tumour heterogeneity and the presence of contaminating stromal cells [53].

There remains the possibility of some artificially modified libraries escaping from this screening, but their effect on the present analysis should be minimized, not to mention that some of them may in fact equalize the expression count, thus making detection of differential expression more stringent.

Using the Power Law Global Error Model (PLGEM) analysis method, selection of significant changes in gene expression is intrinsically more stringent for transcripts with very low expression levels, than for transcripts with high expression levels [11].