However, studies using transgenic mice and more stringent evolutionary criteria demonstrated that a substantial subset of conserved non-coding sequences have transcriptional enhancer activity [13], [18], [19].
Our cutoff is more stringent because the clicker literature demonstrates that student responses improve when they are allowed to discuss their answers with each other over when they work alone (Smith et al. 2011) and the activities encouraged students to work together on the questions.
This apparent power-law scaling does not constitute a proof of self-organized criticality, which should be demonstrated by more stringent statistical tests.
In conclusion, the results of the present study demonstrate community support for more stringent tobacco control policies in Australia.
The present study demonstrates the relevance of employing more stringent inclusion/exclusion criteria in association studies on healthy subjects.
It is demonstrated that this case presents a more stringent test of the applicability of the method than the case of convective heat transfer.
The Clean Air Act allows California to seek a waiver from federal rules if it can demonstrate that its own regulations are more stringent, and needed to address its air pollution problems.
These newer vaccines are more effective in several animal models however, to date only five EBOV vaccine platforms have demonstrated over 80% efficacy in the more stringent NHP model [18] [26].
Interestingly, our observation that these more promiscuous gene families tend to occur predominantly within C2OGs is congruent with a recent study demonstrating that barriers to bacterial HGT are more stringent for single copy genes [35].
If a promulgated standard in a referencing subpart is more stringent than the proposed standard, the owner or operator may choose to demonstrate compliance initially with either the proposed or the promulgated standard.
However, and despite this apparent variation, most of the enriched categories reported by the more stringent tools were included in the ones reported by those tools reporting a larger number of terms, demonstrating the utility of our study strategy.
