Sentence examples for more stringent clinical from inspiring English sources
While similar to the overarching guidelines, the updated guidelines require more stringent clinical testing and immunogenic assessment [ 2].
Second, to maximize the potential to be applied for more stringent clinical study, new and reliable methods for measuring autophagy in clinical samples need to be developed.
Ghent-1 proposed more stringent clinical criteria, which led to the confirmation of MFS in only 32%53%% of patients formerly diagnosed with MFS according to the Berlin nosology.
Because of the biological nature of mAb biotherapeutics, regulatory agencies demand more stringent clinical studies for biotherapeutics than for small molecule drugs due to the potential for adverse immune responses or organ-specific effects [ 2].
As in all-cause dementia analyses, pooled risk estimates for AD based on categorical depression thresholds across 10 studies 21 25 27 34 36 45–47 were higher for more stringent clinical criteria.
With respect to categorical thresholds HRs were pooled across 11 studies 21 25 27 28 30 33–36 and, as expected, risk estimates were higher for more stringent clinical criteria.
Criteria for the usefulness of a "new" discovery should be more stringent in clinical settings [ 31].
In an application where motion in 3D space is equally likely, the requirement for faster image speed becomes ever more stringent for clinical applications.
Improved understanding of pathophysiological mechanisms, in conjunction with more innovative but stringent clinical trial design, will ultimately lead to improved patient outcomes.
A remarkable finding is that multiplex PCR of only 1 mL whole blood reached a sensitivity of 64% compared to 72% for culture using 32 40 mL blood, despite more stringent criteria for clinical relevance in the PCR case.
Therefore, we tried an alternative approach that we consider to be more stringent by analyzing clinical samples for two proteins (LAMP1 and ORP150) not previously associated with pancreatic cancer and found preferential expression in tumors compared to normal tissue in both cases.
