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Data analyses for all tasks were performed using more stringent classification criteria for bilingualism and musician status (Appendix 2 and 3).
Accordingly, we ran three models: the first two used the liberal classification for accuracy (and replicated the models we ran in Experiment 1), and the other examined the more stringent classification, DL.
Further analyses using more stringent classification criteria for bilingualism and musician status were conducted in order to establish that our sample selection criteria for the present study was comparable to that of other literature examining bilinguals and musicians (Bidelman et al., 2013; Paap & Greenberg, 2013).
A more stringent classification that excluded such nodes would have resulted in a more concordant set of gene expression profiles.
However, the lower prevalence (1.1%, 2.9% and 3.7% respectively) of these end-points resulting from the more stringent classification meant that statistical power to detect differences was reduced.
To investigate whether classification sensitivity and specificity could be improved we applied a series of more stringent classification thresholds for the DCC-derived classifier specifically (see Methods).
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A long list of games are banned or censored for the Australian market, as a result of more stringent classifications.
Next we considered whether any factors affected our more stringent accuracy classification, that is, being correct on both the detection and location tasks (DL).
A second model to capture only the patients who fell into the more stringent severity classification (2 or 3 Yes answers) may have resulted in a better performing model but the decision to use the less stringent measure was in line with the parameters for control in the RCP-3Q model.
This may have arisen because of different methods of informing parents (letter vs face-to-face) or due to the more stringent accuracy classification used by Johnson et al. 19 Although it may seem surprising that parents receiving BPC feedback were able to remember more than those who received MI, more structured and specific information is more likely to be remembered.
Clinical remission was defined as a clinical DAI ≤ 2, which even meets a more recent and stringent classification of patient defined endpoints [ 21].
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