Sentence examples for more stable variant from inspiring English sources
Based on the solution structure, we engineered an even more stable variant of CFr by disulfide-induced covalent circularisation that should be an excellent platform for design of novel functions.
A more stable variant of p53 would shift the equilibrium toward the soluble and active form of the protein.
Therefore, dietary supplementation with cysteine, or the more stable variant cystine, can potentially maintain or increase hepatic and intestinal glutathione levels during oxidative stress.
We hypothesized that a more stable variant of Oluc-19 could be created by mutating Asn to either Arg or Lys.
We studied three Nec-1 analogs: Nec-1, the active inhibitor of RIPK1, Nec-1 inactive (Nec-1i), its inactive variant, and Nec-1 stable (Nec-1s), its more stable variant.
Recent work investigated binding of A-Beta to several TTR variants; TTR variants with high amyloidogenic potential bound poorly, whereas more stable variants had a higher affinity for A-Beta [19].
For PCI-34051, two more stable variants exist: PCI-48000 and PCI-48012.
Although the SNPs with an MAF around 0.1 could indicate the presence of even more stable variants, this peak might instead represent transient mutational variants.
In addition, we found mutations at site C (amino acids D113, D115) that gave rise to more stable variants of TrEGI.
26 At the beginning of the pandemic, this instability was advantageous to the virus, but as the pandemic progressed, more stable variants originated.
Interestingly, when we applied the strategy of Blum et al. (2012), who showed that consensus sequences with a rather low cut-off could lead to thermally more stable enzyme variants, Lysine 236 was indeed conserved (at a cut-off of 30%).
