Sentence examples for more stable transcripts from inspiring English sources

Short-lived mRNAs will be induced and turned off more rapidly than will more stable transcripts when transcription increases (4).

SlGolS3 and SlGolS4 genes may generate more stable transcripts since they included AATTAAA motif for polyadenylation signal POLASIG2.

More specifically, cells might employ a rapid switch in transcriptional mode to achieve fast increase in DAT level, hence, rapid synthesis of DAT protein; whereas the production of longer, more stable transcripts prolongs translation time determining basal DAT's level.

Notably, genes of the Rarely expressed class code for more stable transcripts compared to the other two classes).

Using recently developed techniques such as ribonucleoside labeling (Dölken 2013), it may be possible to determine turnover rates on a global scale that will also encompass these more stable transcripts.

In only 31.5 % of the cases (29/92) the reference allele displayed the highest negative energy value, suggesting that the majority of cancer-associated UTR-SNPs lead to more stable transcripts.

Another variant found at the 3' untranslated region, rs10954213, has been reported to create a more functional polyadenlyation site, which creates a more stable transcript [ 101].

Insertions within the 3′ UTR that truncate a transcript such that mRNA-destabilising motifs are removed will give rise to a more stable transcript and, as a result, increased levels of the wildtype protein (see [164]).

Generally, transcripts of housekeeping genes are more stable than transcripts of regulatory genes, which must be rapidly turned over to allow adaptations to changing conditions (Tani, Mizutani, et al. 2012).

Conversely, genes with the lowest ratios of transcriptional activity to steady state levels represent more stable nascent transcripts, and are enriched for structural constituents of the ribosome (P = 6.4 × 10−8) and genes involved in nucleosome assembly (P = 3.6 × 10−4; Table S5).

Unexpectedly, as compared with pcDNA-Luc-Vimentin-psi or pcDNA-Luc-NMHC-psi, pcDNA-Luc-psi seemed to produce more stable mRNA transcripts.