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This occurs by allowing more spontaneous ventilation, which increases venous return.
Various attempts have been made to limit these adverse effects, including daily interruption of infusion of sedatives and analgesics, intermittent bolus injections rather than continuous infusions, and selection of a ventilatory support pattern that allows more spontaneous ventilation.
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The aim of today's approach to mechanical ventilation is generally to achieve more spontaneous breathing and greater use of so-called partial ventilatory assist, whereby the ventilator and the patient share the inspiratory work.
This is most commonly achieved by selecting modes that permit more spontaneous than controlled ventilation [ 61].
Means include daily interruption of infusion of sedatives and analgesics [ 7], intermittent bolus injections rather than continuous infusions [ 8], and selecting ventilatory support that permits more spontaneous than controlled ventilation [ 9], among many others.
In severe lung injury, however, accelerated spontaneous ventilation induced more lung injury than lung-protective mechanical ventilation including muscle paralysis.
Balancing the risks between increasing sedation in order to provide lung protection and allowing spontaneous ventilation in a more awake patient is often a difficult clinical problem with limited applicable evidence.
In this study sample, conventional sleep analysis revealed a better sleep quality during NIV (less fragmentation and a more normal percentage of slow wave sleep, REM sleep, and N1 sleep) than sleep during spontaneous ventilation (Table 4) [ 20].
Life is more spontaneous.
Politically, things were more spontaneous.
That was more spontaneous.
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