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GSCA analysis was therefore supportive of a role for c-MYC in the similarity between leukemic and embryonic stem cell expression signatures, but suggested that TFs more specifically expressed within blood cells also make important contributions to the leukemia stem cell transcriptional program.
In support of this result, expression of a second marker of pre-placodal cells which are more specifically expressed within the olfactory precursor cells, Drosophila distal-less orthologue, dlx3b was also shown to be significantly reduced in hdMO1 embryos (Table 1) (36).
The ParaHox cluster, the hypothetical evolutionary sister of the Hox cluster [15], is also supposed to be part of this ancestral tool-kit, being implicated in endoderm patterning whereas Hox genes are more specifically expressed in ectoderm [16].
In order to delineate if COUP-TFII was more specifically expressed in neurons or astrocytes, we undertook a co-localization study with an astrocyte specific marker, the Glial Fibrilary Acidic Protein (GFAP).
In order to confirm this hypothesis we checked whether genes with cis-eQTL are more specifically expressed in the CNS than others, which indeed is the case (Figure 4).
In general, the flight feather has more specifically expressed genes than the body feather.
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But more neural specifically expressed miRNAs were found in rat tissues in this study.
More genes specifically expressed in liver than spleen and ileum and/or other tissues in human and swine [ 12, 44, 46].
The overview by gender revealed that the female has more genes specifically expressed in individual developmental stages (although only 17,580 common to all stages against 18,257 and 18,151 from the male and hermaphrodite, respectively).
Careful examinations of the genes involved in biological process of these two cDNA libraries revealed that much more genes specifically expressed in the RAMOS cell line were involved in the process of cell differentiation and non-developmental growth, such as aging, death, morphogenesis and pattern speciation, indicating the non-uniformity development of the RAMOS cells.
This distribution is similar to that of known RefSeq genes but more skewed towards specifically expressed loci.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com