More specific trials with improved treatment strategies are needed to underpin the most appropriate choice of physiotherapy intervention.
The presence of this protein appears to be an important prognostic factor and, combined with an age-adjusted International Prognostic Index, could allow researchers to design more specific clinical trials aimed at finding new, more efficacious and less toxic treatments.
RECIST is easier to assess than UCSTS, which may deserve more specific assessment for trials with targeted therapies.
The study also identifies factors influencing elicitation processes and outcomes that could be more specific to the clinical trial context.
First, a short summary on the prevalence, quality, and most commonly cited shortcomings of homeopathic controlled trials in general is presented to support the more specific points within influenza trials alone.
19 22 For a more specific comparison of the different trials, the response of each patient in each trial, both in the placebo group and in the active group, was analysed (figure 3).
A small group of participants (6%) stated that the physical therapists involved in the trial required more specific music, instrumental and musician-specific injury knowledge.
Thus, these meta-analyses have taught us that appropriately sized trials, with more specific patient segregation designed to consider different CVD risk profiles, are warranted to aid more definitive conclusions on the patient group that would likely benefit from aspirin in primary prevention of CVD.
Many of the recent trials have addressed deficiencies of the previous ones with more rigorous trial design, including more specific patient selection criteria (ensure homogeneity of stroke location and severity), stratified randomization algorithms (time-to-treat), narrowed therapeutic time-window and pharmacokinetic monitoring.
The clinical trial setting provides more specific, and sometimes patient-level, resource use and costing data involved in running the interventions, where estimates can be modelled from the costs incurred during the trial itself.
