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Hemorrhagic complications have been reported in some outbreaks, but a more specific symptom is severe arthralgia, often persistent, which results in long-lasting disability.
More specific symptom dimensions derived from the PANSS or BPRS were placed under the respective categories of individual mental functions (e.g. emotional functions or energy and drive functions).
Most patients experience a relative long period with non-psychotic symptoms before their first psychotic episode characterized by unspecific- and more specific symptom constellations (prodrome/Ultra High Risk (UHR) state).
The current work differs from the original LAIDBACK analysis in that we applied more specific symptom definitions that separated LBP from radicular symptoms, corresponding to the distinctions made in actual clinical practice.
This analysis, however, was distinct from that performed previously in that different (and more specific) symptom outcomes were used, with a focus entirely on associations between longitudinal changes in MRI findings and incident symptoms.
In a recent systematic review, we found that for disorders at a given anatomical site (shoulder, elbow or distal arm), more complex case definitions (e.g. involving physical signs, more specific symptom patterns and/or clinical investigations) yielded similar associations with occupational risk factors to simpler definitions based only on broad groups of symptoms [ 7].
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After the first week, more specific symptoms can appear, like a dry cough or severe pneumonia.
An example is multiple sclerosis, which can present with nothing more than transient blurred vision and may take years before other, more specific symptoms appear.
Critics note that the diarrhea, which Tryde cites as the main symptomatic evidence, hardly needs an explanation beyond the general poor diet and physical misery, but some more specific symptoms of trichinosis are missing.
Presently accepted diagnostic criteria for MD [12] are five (or more) specific symptoms having been present during the same two-week period and representing a change from previous functioning; at least one of the symptoms should be either depressed mood or loss of interest or pleasure.
More specific symptoms include drooling, poor oral intake, epistaxis, rhinorrhea, and foul otorrhea.
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