Sentence examples for more specific mutant from inspiring English sources
The results showed that it was possible to use a mutant, ant, with broad effects on plant phenotype to identify genes expressed specifically in ovules, when coupled with predictions from known gene expression patterns, or in combination with a more specific mutant, ino.
These findings might facilitate the design of more potent and specific mutant p53-targeting anticancer drugs.
To make things more complicated, the structural heterogeneity of mutant p53 proteins raises concerns as to the feasibility of designing or identifying therapeutic agents that can rescue more than one specific mutant form of p53 or a subset of mutants.
Thus, using the zebrafish with its rapid developmental period as a laboratory specimen may accelerate genetic screening for more specific KCNQ channel mutants, and perhaps foster drug discovery strategies for chemotherapeutic intervention in diseases associated with mutations in the Kv (x) family of genes, e.g., conditions manifested in humans such as hearing loss, and tinnitus.
The computational model predicted that a drug that specifically binds GTP-bound Ras will have a more specific effect on the mutant than it will on the wild-type system, and thus also on cancerous than on normal tissue.
Thus, genetic analysis of AP2 mutants is more specific for endocytic trafficking of proteins from the cell surface.
The substantial decrease in the catalytic efficiency with NADPH and the retention of the activity with NADH make the H220D mutant 180-fold more specific toward NADH than the wild-type enzyme.
The finding that mutant 468-Ynd1 aspears as two bands, whereas the other mutants and the WT Ynd1 proteins appear as a single protein band (Figs. 3, 4) may result from more pronounced changes in glycosylation of this specific mutant.
A mutant was identified that was 132 times more specific for ABTS.
