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More specific modules are most likely to be found by applying our method using different, specific sets of experiments.
Possible alternative sources of pathway information that might provide better results than the databases used here could be Gene Ontology [ 34] or Reactome [ 35], which provide hierarchical gene sets and pathways, allowing us to move down in the hierarchy to more specific modules if necessary.
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To summarize, we believe that both networks contain valuable information, as the 0.4 clusters reveal more specific gene modules, while the much larger 0.3 network contains more gene modules.
Thus, it appears to be more suitable for finding large functional modules which correspond to general GO terms as opposed to uncovering more specific functional modules.
Alternatively, more specific anxiety modules might be integrated into these treatments to enhance impacts on anxiety.
It is designed to be supplemented with more disease specific modules, which can assess aspects of QOL of particular importance to various patient subgroups [ 17, 28].
This was particularly true for questions that were more specific to the module for students enrolled in the genetics course.
The core section is followed by one or more topic-specific modules.
Strong performance combined with smaller, more specific, and non-overlapping modules, facilitates biological interpretation of these results.
The larger α is, the more specific the derived GO module is.
This analysis shows that signed WGCNA identifies modules with more specific expression patterns than unsigned WGCNA.
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