Future work that includes more species and codon-level analyses, as well as studies of genomic patterns of introgression along hybrid zones, will shed more light on the specific loci that are most important in speciation, species integrity, and adaptation.
The more detailed comparison of specific loci on chromosomes 1S, 1L, 2S, 7S and 9S by Brunner et al. (2005) between Mo17 and B73 showed that colinearity between the genome regions was fragmented due to the insertion of long terminal repeat (LTR) retrotransposons and gene fragments.
SET proteins are involved in both transcription regulation at specific loci and more widespread events such as heterochromatin formation [5].
While other studies have demonstrated a lack of redundant function for two or more Mecps in silencing of specific loci (e.g. [41]), this study provides the first evidence for a redundant function of Mecps in mammalian cells.
Although this may seem highly unlikely, female choice for compatible males may nevertheless occur for specific loci or more restricted regions of the genome, such as the major histocompatibility complex (MHC) in vertebrates [ 89].
For instance, the M-form is identified by loci AG2H135 and AG2H197, the S-form by loci AGXH678, AGXND6U3 and AG2H187, while loci AG2H802 and AG3E34B2 are more specific for Kenya S-form (S3). A. arabiensis is identified by loci AGXH503 and AG2E12D, and A. merus by loci AG2H796 and AG3E40A1.
Since we commenced our clinical surveillance study in 2005, it has been shown that the ecfX locus is more specific than oprL to identify P. aeruginosa from various environmental and clinical extracts [ 30].
Differences in the flaB, glpQ and IGS loci allowed for more specific typing of the B. persica strains, however there were no noticeable differences between human and tick isolates confirming the co-speciation between B. persica and the vector O. tholozani.
Using genetic makers evenly located across the whole genome, researchers can determine where specific loci are shared more often among affected individuals within and between families than would be expected by chance.
Next, we conducted more specific GO analysis of individual query loci, based on inferences from direct assays, mutant phenotype, genetic interaction, physical interaction, expression patterns and traceable author statement.
