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The computational model predicted that a drug that specifically binds GTP-bound Ras will have a more specific effect on the mutant than it will on the wild-type system, and thus also on cancerous than on normal tissue.
The assay panel consisted of 5 whole organism assays measuring apical effects and 14 cell- and organism-based bioassays with more specific effect observations.
There are two effects: the general shift due to the mass of the nucleus, known as the isotope shift, and a more specific effect depending on the magnetic properties of nuclei known as hyperfine structure.
In spite of their benefits they have several side effects, so synthesis of new agonists of these receptors to get more specific effect and better profile of adverse drug reactions is still continued.
In contrast, addition of 50 nM nocodazole, an inhibitor of microtubule polymerization[24], had a more specific effect.
These experiments demonstrate that the UNG2-directed siRNA exhibits a more specific effect than those reported for Vpr.
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The Hermetic tradition also had more specific effects.
It is to be assumed that similar and more specific effects in rehabilitation can be achieved with segment-body vibrations.
However, since both SHH and BMP4 are involved in many biological processes, exemplified by their presence in 11 and 9 respectively of the 14 IPA defined biological function clusters of this study (Table 2), further investigations are needed to pinpoint more specific effect-relationships.
However, the increase in activity was not as significant as that seen upon β-catenin co-transfection, indicating more specific effects of the DNA-binding proteins.
Presumably as the result of a more elaborated electrode placement, we could also obtain our maximal responses at much lower stimulation intensities (about one order of magnitude), which means more specific effects in terms of the elements stimulated.
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