The reviewers are correct, preplay may not reflect a uniform distribution of the multiple experiences the animal had, but rather a more specific distribution of related ones.
Due to the proximity of stages in the CIA gene space, a more specific distribution to each stage is not possible.
For example, Ces1g has a more specific tissue distribution than Ces1d, and is significantly expressed only in the liver and intestine (Quiroga et al., 2012a).
This more specific tissue distribution is likely due to the rapid turnover of any ectopically expressed protein.
Examination of SMR subclass identity by each Bacterial class we surveyed revealed a far more specific SMR distribution than the overall bacterial SMR average indicated in Table 1.
Atf7ip's pattern of expression is consistent with a role in XCI maintenance as in situ hybridization shows that it is ubiquitously expressed in d9.5 embryos with more specific tissue distribution at later time points [ 46].
In contrast, podovirus and siphovirus sequences exhibited more site-specific distributions (Fig. 4).
50 The use of WHR is also supported as it is less strongly associated with BMI than WC, and is thus a more specific surrogate for fat distribution.
To ensure the long-term viability of Cry3Bb1, IRM and IPM practices have been implemented, but these management efforts can be enhanced with a more specific knowledge of the distribution of the resistance alleles.
Even more significantly, it may help identify the biologically relevant topological features that may have been acquired in the course of evolution, which require more specific information than the length distributions to be pinpointed, and hence are not captured by our model.
