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Altogether, we provide resources in the form of an initial curated list of Drosophila RBPs; an RNAi screening library we expect to be used with additional assays that address more specific biological questions; and total ATP and image data useful for comparison of those additional assay results with fundamental information such as effects of a given reagent in the library on cell viability.
While providing a broad genomic perspective, these categories may obscure the influence of more specific biological function on genetic constraint [19] suggesting the need for a more specific biological definition.
In more specific biological terms this situation implies that the gene is either constitutively expressed or under downstream regulatory control by one or more other genes.
In this section we have shown that using node degree alone to predict gene function works strikingly well and that numerous real-life rankings of genes seem to reflect multifunctionality more than any more specific biological principle.
The child of a GO term describes more specific biological meanings than the parent.
Together, these results suggest that anthropocentric thinking is a common cognitive construal used when faced with a lack of more specific biological knowledge.
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We developed our own instrument because we were interested in questions more specific to biological anthropology, and since we were inspired by the studies listed above (e.g., Bishop and Anderson 1986, 1990; Almquist and Cronin 1988; Wilson 2001), we wanted to incorporate many of the same questions.
For more specific cell biological research purpose, probes can be designed to bond with specific organelle of interest and provide guaranteed fluorescence signals.
The topics covered in the chapters range from those concerned with general techniques and concepts that apply to all organisms to others that are more specialized, covering specific biological systems such as viruses, Drosophila, and Homo sapiens.
We wanted to investigate in more detail which specific biological categories associated with chondrocyte differentiation were also down-regulated by PI3K inhibition.
The predicted GO terms are also more specific, yielding deeper biological insight into the role of the TF.
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