Sentence examples for more sparsely methylated from inspiring English sources

Similarly, plant genomes appear to be generally much more sparsely methylated than mammalian genomes.

The most significant difference is that invertebrate genomes tend to be much more sparsely methylated than mammalian genomes.

Densely methylated genes tend to evolve more slowly than sparsely methylated genes (Hunt et al. 2010; Lyko et al. 2010; Park et al. 2011; Sarda et al. 2012; Takuno and Gaut 2012).

Thus, heavily methylated genes, overall, appear to be more conserved at the sequence level than sparsely methylated genes.

Both of these results suggested that densely methylated genes, as a whole, were considerably more conserved at the sequence level than sparsely methylated genes.

Together, these traits indicate that cluster I CGIs most closely fit the original definition of CGIs., In comparison, some CGIs are sparsely methylated in sperm, yet exhibit variable levels of DNA methylation in other methylomes (Cluster II in Fig. 2A).

The seven samples that scored as sparsely methylated for all 16 loci included 4 Stage IIA tumors and 3 Stage IIB samples.

For analysis of each locus, we selected five to six tumor samples that scored as intermediately to densely methylated and five to seven normal breast samples that scored as sparsely methylated.

In sparsely methylated genomes, these values are typically very small.

This method is especially advantageous in the analyses of sparsely methylated genomes with low coverage.

Approximately 2.5 million CGs were sparsely methylated (<10% methylated), approximately 1.8 million CGs were low-methylated (10%to50%0% methylated), and the remaining approximately 15.5 million CGs were highly methylated (>50% methylated) in primary keratinocytes, with similar results for the fibroblasts.