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Then we can fine tune a voice making more sophisticated changes, so we can morph it into a woman's voice, or make it colder and harder".
Modifications to (strept avidins – such as simple amino acid substitutions to reduce biotin binding and alter physico chemical characters – have recently developed into more sophisticated changes, including chimeric (strept avidins, topology rearrangements and stitching of non-natural amino acids into the active sites.
It is reasonable to suppose that more regulatory information enables more sophisticated changes of expression levels, thereby allowing these proteins to work effectively as signaling molecules.
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The behavioural nuances which enable some to embrace change and overcome challenges need to be better understood as this may inform the development of more sophisticated change management strategies that address resistance to change.
Some were more sophisticated and changed their computer's privacy settings (20%) and private browsing modes (20%) and duplicate social networking profiles (9%).
Their music experimented with more sophisticated enhancements like changes in volume and timbre of the guitar, heavier use of lead and rhythm guitars, double-tracked vocals and a frontman who sang and played guitar.
Moving from the current basket of production to a more sophisticated, one requires changes in factor endowments and the production frontier.
For example, more sophisticated users can change settings on their operating system so that no ad networks are contacted, no matter which browser or application is used.
These methods are more sophisticated than fold-change in the sense that they not only consider the average ratios between the groups but also incorporate information on the variation of the measurements and the number of replicates in the experiment.
The government, rather than taking the retrograde step of attempting to push back against that change simply because it causes a few taxation difficulties, must develop a more sophisticated tax policy that changes with it".
(We may introduce the ability to make more sophisticated assumptions about population changes in future versions of the analysis).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com