Sentence examples for more soluble compounds from inspiring English sources
That is why a lot of efforts have been put in surpassing this disadvantage by either obtaining complexes with hydrophilic substances such as cyclodextrins [2] or by derivatising BA to more soluble compounds [3].
Plasma-spray deposited coatings of HA were found to dissolve faster than the stoichiometric HA did because a high temperature melted HA powder and partly decomposed it into more soluble compounds, such as high-temperature ACP and OA (Pezeshki et al. 2010).
At the same time, more soluble compounds tend to be low affinity anesthetics, thus expanding the screen to increase compound concentrations (by delivering double the amount of compound via two successive pin transfers) is not considered a productive strategy.
Thus, various functionalizations were and are being exploited to get more soluble compounds capable to interact with biological systems.
We therefore derivatised one of the more soluble compounds (1acc) with a fluorescein label to give FITC-Gly-1acc and performed a direct binding experiment with hDM2 this afforded a dissociation constant of 760 (±140) nM and confirmed strong interaction with the target protein.
In subsequent validation screens we took advantage of the newer compound as it is a more soluble compound.
For the most part, hepatic metabolism comprises the largest component of nonrenal clearance, typically converting medications to less toxic and more water soluble compounds to facilitate elimination from the body.
Sulfotransferase enzymes including SULT2A1, SULT2B1 and SULT1A1 are associated with metabolic clearance of androstenone and skatole since they are known to conjugate steroid hormones and drugs into more water soluble compounds that facilitates excretion [ 12, 15- 20].
It is noticeable that if ACD3 and MDDR1 have similar MW distributions, MDDR1 compounds are more soluble than ACD3 compounds.
Monoesters and oxidative metabolites can be excreted unchanged or can undergo glucuronidation in a phase II biotransformation to a more water soluble compound [ 9, 10].
They are capable of converting a variety of electrophilic and hydrophobic compounds into more soluble, more easily excretable compounds through catalyzing them in conjunction with glutathione [ 10].
