Moreover, if we are to learn from the two manipulations most reliably known to increase mouse lifespan, loss of GH / IGF-I signals and dietary restriction, we'd walk away the notion that, at a systemic level, decreased expression of certain HSP-encoding genes (e.g., Hsph1) is associated with longevity more so than increased HSP expression [ 28, 39].
Thus the observed increases in β2S1 expression in BPD in Figure 4A were led by increased expression by the MM genotype more so than any increased expression by the Mm or mm genotype, whereas the observed decreases in β2S2 expression in BPD and SCZ were led by decreased expression by the Mm genotype more so than any decreased expression by the MM or mm genotype.
That is easy and harmless, much more so than prescribing or increasing doses of medications.
It is this shape compatibility, more so than an increase in the number or quality of interactions between the chemical groups that make up the proteins, that enables LapD to bind to LapG.
However, the rates associated with this mechanism are necessarily high enough such that the increase in heteroplasmy variance is very sharp, notably more so than the smooth increase with time observed in experiment (see, e.g., Figure 2 in the Main text).
Tara Coumbe, from Gibraltar, outlined a similar dissatisfaction with the hyped up debates, saying 'I think it's been quite petty and I haven't learnt anything from any of the debates so far.' Many of those interviewed also recognised the huge role the media has been playing in this election, perhaps more so than ever before with the increased engagement through social media.
The 24-h urinary Na+ significantly increased with enalapril, more so than isradipine.
As many economists have indicated, eliminating government shortfalls through spending reductions tends to benefit the economy more so than by eliminating them through tax increases.
He mentioned that America has increased their activeness in foreign affairs, more so than ever.
