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The Jukes-Cantor distances still provide a much faster rate of nucleotide substitution in Riesia (12.9 23.9% per 50 My), and it is important to note that this more simplistic model of molecular evolution underestimates the substitution rate by 30%.
These observations suggest that DNA sequence and methylation state work together with transcriptional state to ensure correct targeting of histone lysine methylation marks, rather than a more simplistic model where DNA sequence alone influences the placement of histone marks.
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More simplistic models have too often obscured this cardinal lesson.
The use of more simplistic models of nucleotide substitution for both concatenation and species tree reconstruction methods leads to the artefactual grouping of turtles and crocodiles, most likely because of substitution saturation at third codon positions.
Thorough taxon sampling allows the use of more simplistic models of evolution, because multiple changes at each nucleotide site can be appropriately reconstructed through the increased sampling of the tree [ 18].
We used an extended dataset of mitochondrial protein genes to reevaluate the phylogeny of Cnidaria, paying attention to common biases in phylogenetic reconstructions resulting from insufficient taxon sampling and using more simplistic models of sequence evolution.
While, the US admissions system is vastly different to the more the more simplistic UK model- students have to sell themselves to their desired college and talk-up their impressive extracurricular activities- students are becoming more and more prepared to devote hours to applications.
Mr. Koppelman said he thought Ms. Harris Millard's "opportunity and our desire for a more streamlined, simplistic model will fit everybody".
In Manjit Bawa's "Modern Miniature" (2000), what the exhibition's curator calls "abstract zones" common to traditional Indian painting and a more Modernist simplistic modeling of forms are married successfully.
The modulation of the intrinsic APD heterogeneity due to electrotonic interactions at the tissue level uncovered here, and its further reduction during higher pacing frequencies, agree with the findings from previous simulation studies on more anatomically simplistic models (15, 20, 21, 42).
These observations challenge the more simplistic Warburg effect models and suggest that the coordination of glycolysis and mitochondrial pathways is important for tumor growth.
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